Frame Rates in 3D vs 2D

This is a rather obvious difference between 2D and 3D animation. It is far more easy to animate at an incredibly high frame rate with 3D, because the actual process of animating involves mainly tweening, whereas with 2D is mostly drawing, and depending on what software is used for 2D, can involve tweening but too much of it would lessen the quality of the animation. The average frame rate for 3D animation is 24-30 fps, but occasionally, specifically with video games, the frame rate will reach heights such as 60 fps, or even 144 fps! No 2D animator would ever be crazy enough to attempt such high frame rates. There would be no point, since 2D animation will look smooth enough without a high frame rate, because due to the simple and solid look of it, it'll give the illusion of smoothness; that's why in Japan they can get away with animating 2D at a mere 8-12 fps. I personally adore high frame rates in animation, because they just give the animation a lot of character, and adds a unique quality to the technique that makes it stands out among every other technique of film and TV. Just look at this footage of Resident Evil Remastered, for example.

Even though the art style is realistic, the high frame rate makes it look very appealing and separates it from the more standard 3D animations of that style that are animated at the average 30fps to look more "cinematic".